Study of in-vivo breast cancer in a subcutaneous xenograft mouse model using terahertz imaging
Received:September 26, 2019  Revised:August 16, 2020  download
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Author NameAffiliationE-mail
Wu Limin Institute of Laser and Optoelectronics, School of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Key Laboratory of Optoelectronics Information Technology (Ministry of Education), Tianjin University, Tianjin 300072, China 
wulimin@tju.edu.cn 
Liao Bin Institute of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing
400038, China 
 
Xu Degang Institute of Laser and Optoelectronics, School of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Key Laboratory of Optoelectronics Information Technology (Ministry of Education), Tianjin University, Tianjin 300072, China 
xudegang@tju.edu.cn 
Wang Yuye Institute of Laser and Optoelectronics, School of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Key Laboratory of Optoelectronics Information Technology (Ministry of Education), Tianjin University, Tianjin 300072, China
Institute of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing
400038, China 
yuyewang@tju.edu.cn 
Ge Meilan Institute of Laser and Optoelectronics, School of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Key Laboratory of Optoelectronics Information Technology (Ministry of Education), Tianjin University, Tianjin 300072, China 
meilange@tju.edu.cn 
Zhang Chaonan School of Life Sciences, Tianjin Engineering Center of Micro-Nano Biomaterials, Tianjin University, Tianjin 300072, China zhangchaonan@tju.edu.cn 
Li Jiahua School of Life Sciences, Tianjin Engineering Center of Micro-Nano Biomaterials, Tianjin University, Tianjin 300072, China lijiahua@tju.edu.cn 
Sun Zhongcehng Institute of Laser and Optoelectronics, School of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Key Laboratory of Optoelectronics Information Technology (Ministry of Education), Tianjin University, Tianjin 300072, China 
sun92@tju.edu.cn 
Chen Tunan Institute of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing
400038, China 
ctn@tmmu.edu.cn 
Feng Hua Institute of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing
400038, China 
fenghua8888@aliyun.com 
Yao Jianquan Institute of Laser and Optoelectronics, School of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China
Key Laboratory of Optoelectronics Information Technology (Ministry of Education), Tianjin University, Tianjin 300072, China 
jqyao@tju.edu.cn 
Abstract:Breast cancer (BC) is one of the most common diseases in women. The accurate detection for BC is very important in clinical practice. In this paper, in-vivo breast cancer in a subcutaneous xenograft mouse was studied with the continuous-wave terahertz (THz) reflection imaging system at 2.52THz. The high reflection region in THz images of in-vivo subcutaneous xenograft mouse corresponded well to the tumor area in visible. The difference value of 15% between tumor and normal tissues was observed. For the gold standard, the tumor areas at different depths from the surface of skin in mouse model were obtained by hematoxylin and
keywords:Breast cancer  continuous terahertz wave  reflection imaging
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Copyright:《Journal of Infrared And Millimeter Waves》