Study of in-vivo breast cancer in a subcutaneous xenograft mouse model using terahertz imaging
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1.Institute of Laser and Optoelectronics, School of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China;2.Key Laboratory of Optoelectronics Information Technology (Ministry of Education), Tianjin University, Tianjin 300072, China;3.Institute of Neurosurgery, Southwest Hospital, Army Medical University, Chongqing;400038, China;4.School of Life Sciences, Tianjin Engineering Center of Micro-Nano Biomaterials, Tianjin University, Tianjin 300072, China

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TN29

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    Abstract:

    Breast cancer (BC) is one of the most common diseases in women. The accurate detection for BC is very important in clinical practice. In this paper, in-vivo breast cancer in a subcutaneous xenograft mouse was studied with the continuous-wave terahertz (THz) reflection imaging system at 2.52THz. The high reflection region in THz images of in-vivo subcutaneous xenograft mouse corresponded well to the tumor area in visible. The difference value of 15% between tumor and normal tissues was observed. For the gold standard, the tumor areas at different depths from the surface of skin in mouse model were obtained by hematoxylin and

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Wu Limin, Liao Bin, Xu Degang, Wang Yuye, Ge Meilan, Zhang Chaonan, Li Jiahua, Sun Zhongcehng, Chen Tunan, Feng Hua, Yao Jianquan. Study of in-vivo breast cancer in a subcutaneous xenograft mouse model using terahertz imaging[J]. Journal of Infrared and Millimeter Waves,2020,39(5):553~560

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History
  • Received:September 26,2019
  • Revised:August 16,2020
  • Adopted:June 08,2020
  • Online: August 13,2020
  • Published: