The applications of infrared thermal imaging (IRTI) in disease prevention are summarized. The coherence point between IRTI and Tradition Chinese Medicine (TCM) is found. By browsing the latest literatures at home and abroad, the applications of IRTI in disease prevention are understood. The result shows that IRTI has a high coherence point with the theory of TCM in holism concept and eight-principle syndrome differentiation. IRTI has exhibited a strong advantage in combination with the disease prevention of TCM and has better complementarity with TCM. This technology has been widely used for physical identification, health management of chronic diseases, TCM syndrome differentiation and evaluation of treating efficacy in the `Disease Prevention'' project. It is helpful to the disease intervention of those who have chronic disease and subhealth etc so as to achieve the goal of targeted therapy. Although the `Disease Prevention'' project has made some progresses, some shortcomings still exist. For instance, the current physical identity lacks certain objectivity, the whole process takes a long time and the physique classification is unreasonable etc. IRTI is more objective and scientific in physical identification. So, it has a broad application prospect in the `Disease Prevention'' project.