To investigate whether β-carotene has a phase change under high pressure, high pressure Raman spectroscopy of β-carotene in the range of 0 to 30 Gpa pressure was performed. By evaluating the linear function change of Raman spectral frequency-pressure in different pressure ranges, whether or not a phase transition occurs can be determined. The study shows that when the pressure rises to about 7 Gpa and 14 Gpa, the frequency-pressure linear function equation of β-carotene molecules changes, which means that the phase transition occurs. To analyze whether the frequency-pressure linear relationship is changed is a simple and convenient technical method for judging whether the phase shift is changed. The study of stress phase transition of neat β-carotene has not been reported.