The mid-wavelength infrared radiation characteristics of turbojet engine powered missiles are studied. The calculation models of radiation intensity of exhaust nozzle, exhaust plume and skin of an antiship missile are established respectively. The influence of exhaust plume on nozzle radiation and plume radiation is considered. The attenuation characteristics of infrared radiation in atmosphere in the 3 to 5 μm waveband are analyzed by using the MODRTAN software. Finally, the theoretical calculation result is compared with the experimental result. The results show that the established calculation models and methods can simulate the infrared radiation characteristics of antiship missiles at different detection angles.