According to the practical requirements of the phase transition temperature close to room temperature, the good infrared transmission adjustment ability and high visible light transmittance of the VO2 layer stacks for smart windows, a high performance smart window layer stack composed of a tungsten-doped VO2 layer and a SiO2 antireflection layer is designed by using a CODE (Coating designer) software. The influence of the thickness of each layer on its infrared transmission adjustment ability and visible light transmittance is studied systematically. The layer stack composed of glass/70 nm tungsten-doped VO2/50 nm SiO2 is found to have the best comprehensive performance. It is prepared by using a large area magnetron sputtering system. The experimental measurement result shows that it has a phase transition temperature of 38.2℃, an infrared transmission adjustment ability of 40.4% and a peak visible light transmittance of 46.3%. In the infrared band of sunlight, it has good incident radiation adjustment effectiveness. Moreover, the preparation method of the layer stack is compatible to the current large area glass coating process. So, it is suitable for industrial production.