A 4-channel detector imaging circuit based on a CCD47-20 and a CCD55-30 is designed. Because of long integration time, the system can implement high sensitivity imaging under the low-light condition. To choose appropriate driving devices, the driving circuit model for the detector is established and the driving requirements of CCD detectors are analyzed. After the noise characteristics of the detectors are analyzed, the circuit noise is suppressed by using the Correlated Double Sampling (CDS) and a reasonable filter. The noise interference among the 4 channel signal processing circuits is compared. The result is helpful to the reasonable PCB routing. This imaging circuit is used with a commercial camera lens and low noise images are obtained successfully under the low-light condition.