The influences of pressure, power and time on the welding quality of the first joint of ultrasonic wedge welding and thermosonic bonding are studied based on practical application. The welding quality is determined according to the tension values measured by the tension tester, and the technological parameters satisfying the quality requirements of wedge and ball welding of detector chips are given. The overall welding quality is improved as well. In addition, two reinforcing methods after thermosonic bonding are studied, and the effects of the two methods are compared.