Whether Infrared Thermography (IRT) can be used as one of the methods to evaluate the therapeutic effect of Gout is discussed. A multicenter, randomized, controlled trial design is adopted, and 60 gout patients with dampness heat accumulation syndrome are selected. Then they are divided into experimental group and control group (30 cases in each group). The experimental group is given Zhuye Shigao Decoction granules orally, 1 bag/time, 3 times a day; the control group is given celecoxib capsule orally, 200 mg/time, once a day. Both groups take 7 days as a course of treatment. After the course of treatment, the changes of UA, CRP and infrared calorific values before and after the treatment of the two groups are observed. The results show that the CRP and infrared calorific value of both groups are improved(P<0.01).IRT is of great significance in evaluating the therapeutic effect of gout.