The role of infrared thermal imaging technology in the etiology and pathogenesis of hyperuricemia was discussed. A retrospective study was performed on 300 patients diagnosed with hyperuricemia. A whole body scan was performed using HIR-2000 infrared thermal imager. The deviation of coldness and heat in the abdomen and renal area was recorded. There were 246 cases with the abdomen coldness deviation, accounting for 82%. There were 273 cases with the renal coldness deviation, accounting for 91%. The results show that infrared thermography plays an important role in the etiology and pathogenesis of hyperuricemia. It can be widely used in the diagnosis, treatment and prevention of hyperuricemia.