To meet the requirements of a satellite platform, the lightweight design is needed for a certain electronic control cabinet. The structure style of a small, light and highly stable electronic control cabinet is given. According to the complex operation condition of electronic devices of remote sensors in orbit, a protective design method for electronic control cabinets is proposed. An active thermal control measure is taken for high power consumption devices. Finally, the electronic control cabinet is analyzed by using the Finite Element Method (FEM). The result shows that the first-order modal of the electronic control cabinet is 240 Hz which is much greater than the specification of 140 Hz and can meet the requirements of space application.