Abstract:Functional near-infrared spectroscopy (fNIRS) is noninvasive, portable, and suitable for measurements in natural environments. However, it still faces problems in practical measurements, including weak signals, difficulty in high-speed synchronous multi-channel acquisition, and inter-channel crosstalk. Therefore, this paper constructed a code-division photon-counting fNIRS system and designed a parallel measurement method based on code division multiple access. The system achieved high-sensitivity, low-crosstalk, high-speed synchronous multi-channel acquisition. Based on this system, this paper combined a steady-state visual evoked experimental paradigm to measure the hemodynamic responses of the visual cortex in myopic subjects under uncorrected and optically corrected conditions. It analyzed resting-state functional connectivity, task-related brain activation, and task-induced spatiotemporal dynamic features. The results show that the system can stably acquire multi-channel weak hemodynamic signals from the visual cortex and supports multidimensional characterization of brain functional response features under different visual conditions.