Based on the actual needs of shipborne air defense missile development, the infrared radiation characteristics of Naval Strike Missile (NSM) attacking at low altitude are deeply studied, and the physical model of NSM anti-ship missile is established. The NSM anti-ship missile model is meshed by ICEM software. The temperature and infrared radiation brightness distribution of NSM anti-ship missile are simulated by CFD software. Finally, the infrared radiation intensity of NSM anti-ship missile at different detection angles is analyzed and calculated by the reverse Monte Carlo method, which provides support for the evaluation of interception capability of ship-borne air defense missiles at different angles.