压缩倾角薄层光学层析成像系统
Received:March 26, 2016  Revised:September 27, 2016  点此下载全文
引用本文:赵会娟,贾梦宇,秦转萍,王爽,陈雪颖,李娇,张林,高峰.压缩倾角薄层光学层析成像系统[J].Journal of Infrared and Millimeter Waves,2016,35(6):688~693
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Author NameAffiliationE-mail
ZHAO Hui-Juan College of Precision Instruments Optoelectronics Engineering,Tianjin University huijuanzhao@tju.edu.cn 
JIA Meng-Yu College of Precision Instruments Optoelectronics Engineering,Tianjin University  
QIN Zhuan-Ping Tianjin Key Laboratory of Information Sensing and Intelligent Control qinzhuanping@126.com 
WANG Shuang College of Precision Instruments Optoelectronics Engineering,Tianjin University  
CHEN Xue-Ying College of Precision Instruments Optoelectronics Engineering,Tianjin University  
LI Jiao College of Precision Instruments Optoelectronics Engineering,Tianjin University  
ZHANG Lin College of Precision Instruments Optoelectronics Engineering,Tianjin University  
GAO Feng College of Precision Instruments Optoelectronics Engineering,Tianjin University gaofeng@tju.edu.cn 
基金项目:国家自然科学基金[81271618,S81371602,S61475115,S61475116,S81401453,S61575140,S81571723]; 天津市自然科学基金[13JCZDJC28000,S14JCQNJC14400,S15JCZDJC31800,S15JCQNJC14500];天津职业技术师范大学校科研发展基金[KYQD14007]
中文摘要:首先研究了LOT中光线倾斜角度对光在组织体内分布的影响, 在此基础上设计并完成了压缩倾角薄层光学层析成像(cdaLOT)系统, 提出了矫正扫描振镜枕型畸变的新方法, 并发展了基于虚拟源-扩散近似技术和GPU的LOT快速图像重建算法.光路模拟结果表明, cdaLOT系统可使入射主光线倾角减小为传统LOT系统的1/2.cdaLOT系统将测量值与蒙特卡洛模拟结果的相对误差由传统系统的38%降低为18%, 从而缓解了实际测量方式和正向数学模型的不匹配性.仿体成像实验表明: 重建异质体的吸收系数、位置和形状与真实情况基本相符.
中文关键词:薄层光学层析成像  倾角  图像重建  测量系统
 
Laminar optical tomography system with condensed dip-angle
Abstract:The influence of the dip angle on light distribution inside tissue was investigated. Based on the investigation, a LOT system with condensed dip-angle (cdaLOT) over the whole detection range was developed. A new method for correcting the deflection-angle of galvanometer mirrors was also proposed. A fast image reconstruction algorithm for LOT was also developed based on the virtual-source diffusion approximation and GPU. Light path simulation showed that the developed cdaLOT system decreased the dip angle of the incident light to 1/2 of that of the traditional LOT system. The relative deviation of the measured data to MC results was about 18% for cdaLOT while that for traditional LOT was as large as 38%. Reconstructed images showed that the reconstructed absorption coefficient, and the position and shape of the inhomogeneity coincided with the real target.
keywords:laminar optical tomography, dip angle, image reconstruction, measurement system
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