A new method to calibrate CCD camera was proposed. It consists of two-dimension rotate instrument, collimator and CCD camera. At first, through Hough translation and least squares image matching, the intersection point of crisscross fixed on collimator, which imaged on the CCD focus plane, was found, And then a linear regression of least squares was used to calibrate the inner orientation elements and the distorted parameters based on the non-linear distortion model of camera. Experimental results of this method reveal good performance in the application of aerial triangulation operation and digital mapping.