Laser dazzling is important for countermeasures of precision guided weapons and self defence. In this study, the damages of high-power CO2 laser to long-wave infrared (LWIR) HgCdTe detector were studied theoretically and experimentally. Based on the results of experiment, the relationship between he temperature-rise of detectors and the time of laser irradiation on the detector and the power of laser was calculated by using the theoretical model of temperature-rise .The theoretical results demonstrate that the interference threshold of the detector is 16.5W/cm2 and the damage threshold is 126W/cm2. The conclusions have a reference value for laser jamming satellite-based detector.