太赫兹波与拉曼光谱技术在脑创伤检测中的应用研究
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作者单位:

1.天津大学 精密仪器与光电子工程学院激光与光电子研究所,天津 300072;2.天津大学 光电信息技术教育部重点实验室,天津 300072

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中图分类号:

O43

基金项目:

国家自然科学基金 (No.62175182,No.U22A20353,No.62275193,No.U22A20123)


Terahertz wave and Raman spectroscopy technology application in traumatic brain injury
Author:
Affiliation:

1.Institute of Laser and Optoelectronics, School of Precision Instruments and Optoelectronics Engineering, Tianjin University, Tianjin 300072, China;2.Key Laboratory of Optoelectronic Information Technology (Ministry of Education), Tianjin University, Tianjin 300072, China

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    摘要:

    脑创伤是危害人类健康最严重的疾病之一,灵敏快速的检测方式是对其进行准确有效治疗的有力保障。太赫兹波和拉曼光谱技术因其在技术上的互补性,在生物医学诊断等领域有着广泛的应用前景。本文针对脑创伤检测方面的需求和难点,总结了太赫兹波和拉曼光谱技术在脑创伤检测中的应用研究。首先介绍了太赫兹成像技术与光谱技术的发展现状,并分别介绍了两种技术在脑创伤检测中的应用研究;除此之外,文章概述了拉曼光谱的原理及分类,并讨论了拉曼光谱技术在脑创伤组织、体液及生物标志物检测中的研究进展。最后,文章对太赫兹波与拉曼光谱技术在脑创伤的检测中的发展趋势进行了分析,为太赫兹波与拉曼光谱技术应用于脑创伤的快速、准确诊断中提供了新的研究思路。

    Abstract:

    Traumatic brain injury is one of the most serious diseases that endanger human health. Sensitive and rapid detection method is a kind of powerful guarantee for the accurate and effective treatment of traumatic brain injury. In recent years, terahertz (THz) wave and Raman spectroscopy have broad application prospects in biomedical diagnosis and other fields due to their complementarity in technology. In this article, the researches of terahertz wave and Raman spectroscopy technology in traumatic brain injury detection were summarized in response to the needs and difficulties of traumatic brain injury diagnosis. Firstly, the development status of THz imaging and THz spectroscopy technology were introduced, and the applications of the two technologies in traumatic brain injury detection were also introduced, respectively. In addition, the principle and classification of Raman spectroscopy were summarized, and the researches of Raman spectroscopy in the detection of traumatic brain injury tissues, body fluids and biomarkers were discussed. Finally, the development trend of THz wave and Raman spectroscopy in the detection of traumatic brain injury was analyzed, which provides a new research idea for the application of THz wave and Raman spectroscopy in the rapid and accurate diagnosis of traumatic brain injury.

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  • 收稿日期:2025-02-05
  • 最后修改日期:2025-02-27
  • 录用日期:2025-03-11
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