压缩倾角薄层光学层析成像系统
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天津大学 精密仪器与光电子工程学院,天津大学 精密仪器与光电子工程学院,天津市信息传感与智能控制重点实验室,天津大学精密仪器与光电子工程学院,天津大学精密仪器与光电子工程学院,天津大学精密仪器与光电子工程学院,天津大学精密仪器与光电子工程学院,天津大学精密仪器与光电子工程学院

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国家自然科学基金[81271618,S81371602,S61475115,S61475116,S81401453,S61575140,S81571723]; 天津市自然科学基金[13JCZDJC28000,S14JCQNJC14400,S15JCZDJC31800,S15JCQNJC14500];天津职业技术师范大学校科研发展基金[KYQD14007]


Laminar optical tomography system with condensed dip-angle
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College of Precision Instruments Optoelectronics Engineering,Tianjin University,College of Precision Instruments Optoelectronics Engineering,Tianjin University,Tianjin Key Laboratory of Information Sensing and Intelligent Control,College of Precision Instruments Optoelectronics Engineering,Tianjin University,College of Precision Instruments Optoelectronics Engineering,Tianjin University,College of Precision Instruments Optoelectronics Engineering,Tianjin University,College of Precision Instruments Optoelectronics Engineering,Tianjin University,College of Precision Instruments Optoelectronics Engineering,Tianjin University

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    摘要:

    首先研究了LOT中光线倾斜角度对光在组织体内分布的影响, 在此基础上设计并完成了压缩倾角薄层光学层析成像(cdaLOT)系统, 提出了矫正扫描振镜枕型畸变的新方法, 并发展了基于虚拟源-扩散近似技术和GPU的LOT快速图像重建算法.光路模拟结果表明, cdaLOT系统可使入射主光线倾角减小为传统LOT系统的1/2.cdaLOT系统将测量值与蒙特卡洛模拟结果的相对误差由传统系统的38%降低为18%, 从而缓解了实际测量方式和正向数学模型的不匹配性.仿体成像实验表明: 重建异质体的吸收系数、位置和形状与真实情况基本相符.

    Abstract:

    The influence of the dip angle on light distribution inside tissue was investigated. Based on the investigation, a LOT system with condensed dip-angle (cdaLOT) over the whole detection range was developed. A new method for correcting the deflection-angle of galvanometer mirrors was also proposed. A fast image reconstruction algorithm for LOT was also developed based on the virtual-source diffusion approximation and GPU. Light path simulation showed that the developed cdaLOT system decreased the dip angle of the incident light to 1/2 of that of the traditional LOT system. The relative deviation of the measured data to MC results was about 18% for cdaLOT while that for traditional LOT was as large as 38%. Reconstructed images showed that the reconstructed absorption coefficient, and the position and shape of the inhomogeneity coincided with the real target.

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赵会娟,贾梦宇,秦转萍,王爽,陈雪颖,李娇,张林,高峰.压缩倾角薄层光学层析成像系统[J].红外与毫米波学报,2016,35(6):688~693]. ZHAO Hui-Juan, JIA Meng-Yu, QIN Zhuan-Ping, WANG Shuang, CHEN Xue-Ying, LI Jiao, ZHANG Lin, GAO Feng. Laminar optical tomography system with condensed dip-angle[J]. J. Infrared Millim. Waves,2016,35(6):688~693.]

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  • 收稿日期:2016-03-26
  • 最后修改日期:2016-09-27
  • 录用日期:2016-05-09
  • 在线发布日期: 2016-12-06
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