生物组织脱水过程的太赫兹时域光谱
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南京医科大学基础医学院;江苏盛泽医院肿瘤中心,中国科学院上海应用物理研究所,中国科学院上海应用物理研究所,上海理工大学上海市现代光学系统重点实验室,南京医科大学基础医学院

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中国科学院知识创新项目;国家自然科学基金项目(面上项目,重点项目,重大项目)


The dehydration processes of biological tissues investigated by terahertz time-domain spectroscopy
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School of Basic Medical Sciences,Nanjing Medical University,Shanghai Institute of Applied Physics,Chinese Academy of Sciences;Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Shanghai Institute of Applied Physics,Chinese Academy of Sciences,Engineering Research Center of Optical Instrument and System,University of shanghai for Science and Technology,School of Basic Medical Sciences,Nanjing Medical University

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    摘要:

    利用透射式太赫兹时域光谱(THz-TDS)技术对猪脂肪、肌肉和皮肤三种新鲜组织的持续脱水过程进行在线连续扫描,观察太赫兹波时域谱在组织脱水过程的变化,并分析比较三种组织脱水前后的太赫兹波吸收系数及折射率的改变及差异.结果表明,太赫兹波对新鲜组织含水量的改变十分敏感,新鲜组织的含水量是影响太赫兹波吸收系数的主要因素.同时,不同组织对太赫兹的吸收有明显差异,表明太赫兹光谱技术可以鉴别不同的组织类型.本研究为太赫兹技术在生物医学领域的进一步研究和应用提供了帮助.

    Abstract:

    The continuous dehydration processes of adipose, muscle and skin from pork were investigated by transmitted terahertz time-domain spectroscopy (THz-TDS). The changes of terahertz spectroscopy during the dehydration have been observed, and the difference of absorption coefficient and refractive index at the beginning and end of the dehydration among three biological tissue samples were compared. The results show that terahertz spectroscopy is sensitive to the change of water content in the fresh tissues, and water content is the primary factor to influence the absorption coefficient of fresh tissues. Moreover, there are significant differences in the absorption of the terahertz spectroscopy for different tissues, indicates that the transmitted THz-TDS enable to distinguish different biological tissues.

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杨航,赵红卫,张建兵,朱亦鸣,刘永彪.生物组织脱水过程的太赫兹时域光谱[J].红外与毫米波学报,2014,33(3):263~267]. YANG Hang, ZHAO Hong-Wei, ZHANG Jiang-Bing, ZHU Yi-Ming, LIU Yong-Biao. The dehydration processes of biological tissues investigated by terahertz time-domain spectroscopy[J]. J. Infrared Millim. Waves,2014,33(3):263~267.]

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  • 收稿日期:2013-04-12
  • 最后修改日期:2013-05-02
  • 录用日期:2013-05-06
  • 在线发布日期: 2014-07-30
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