With the development of infrared imaging guided weapons, the performance of the infrared target simulators for simulation experiment is improved. Now, the infrared polarization imaging technology is becoming mature and the detection systems and guided weapon based on infrared polarization imaging are also being developed. According to the polarization generation and modulation technologies, several infrared polarization imaging simulation systems which are able to provide polarization information from targets to the detection systems and guided weapon based on polarization imaging are discussed.