With the development of infrared countermeasure technologies, the design of infrared imaging precision guided weapons meets more and more practical difficulties. To improve the adaptability of infrared imaging precision guided weapons in a complicated battle field, the characteristics of targets are studied by using the main-in-the-loop technology in practical projects. A project scheme which can provide support for the criteria optimization of Auto Target Recognition (ATR) is proposed. The scheme is of referential value to the improvement of the independent design ability of the infrared imaging precision guided weapons in our country.