The environment of modern warfare is becoming more and more complex, and the single guidance mode is vulnerable to effective interference, while the composite seeker can exploit the advantages of various guidance modes and make them complement each other. According to the technical characteristics of infrared imaging sensor, active millimeter-wave radar and passive radar, the work processes of infrared imaging/active millimeter-wave radar composite seeker and infrared imaging/passive microwave composite seeker are analyzed. In order to improve the anti-nterference ability of composite seeker, by combining with the actual process of anti-ship missile, millimeter-wave radar or passive radar is used at long distance, while infrared target features are exploited to distinguish between interferences and ship targets at short distance, forming a terminal guidance strategy suitable for infrared imaging/active millimeter-wave radar composite seeker and infrared imaging/passive microwave composite seeker of anti-ship missiles.