The virtual reality technology is used in the simulation of opto-electronic measures. An aero-plane opto-electronic countermeasure simulation system is constructed by using the simulation modeling software, Multigen Creator, and the scene management software, OpenGVS. Some key problems such as modeling of targets, choice of viewpoint, collision detection and explosion effectiveness which should be solved when using OpenGVS to develop the opto-electronic countermeasure software are presented. Finally, the interference of infrared interference bombs is evaluated according to the developed simulation platform.